RT Journal Article
T1 Prevalence and risk factors associated with systemic hypertension in dogs with spontaneous hyperadrenocorticism
A1 García San José, Paula
A1 Arenas Bermejo, Carolina
A1 Clares Moral, Irene
A1 Cuesta Álvaro, Pedro
A1 Pérez Alenza, María De Los Dolores
AB Background: Systemic hypertension (SH) is common in dogs with hyper-adrenocorticism (HAC) however there are not many studies assessing its prevalenceand risk factors.Objectives: To determine the prevalence and severity of SH in dogs with HAC andits association with clinical and laboratory findings to identify potential risk factors.Animals: Sixty-six client owned dogs with spontaneous HAC.Methods: Retrospective cross-sectional study. Medical records of dogs with HACwere reviewed. Systolic blood pressure (SBP) was measured using Doppler ultraso-nography. Clinical signs, physical examination findings and clinicopathologic data(CBC, serum biochemistry and electrolytes, urinalysis and urinary culture, and adrenalfunction tests) were reviewed for analysis.Results: Prevalence of SH (≥150 mm Hg) was 82% (54/66) and prevalence of severeSH (≥180 mm Hg) was 46% (30/66). All dogs with thrombocytosis had SH (P = .002),and a platelet count ≥438 × 103 /μL was 100% specific and 61.1% sensitive to predictSH (AUC = .802, P = .001). Median potassium levels were lower in hypertensive dogs(4.1 mEq/L, range 3.1-5.4 mEq/L) than in normotensive ones (4.5 mEq/L, range 4.0-5.0 mEq/L) (P = .007). Dogs with UPC ≥ 0.5 had higher median SBP than those with-out proteinuria (P = .03). Dogs with concurrent diabetes mellitus seemed to have areduced risk of SH (OR = .118, 95%CI = .022-.626, P = .02).Conclusions and Clinical Importance: Systemic hypertension is common in dogs withHAC and is frequently severe. Blood pressure should be routinely assessed in these dogs,especially if thrombocytosis, proteinuria or low potassium concentrations are present.
PB Wiley
YR 2020
FD 2020-09-02
LK https://hdl.handle.net/20.500.14352/107255
UL https://hdl.handle.net/20.500.14352/107255
LA eng
NO García San José P, Arenas Bermejo C,Clares Moral I, Cuesta Alvaro P, Pérez Alenza MD. Prevalenceand risk factors associated with systemic hypertension in dogswith spontaneous hyperadrenocorticism. J Vet Intern Med.2020;34:1768–1778. https://doi.org/10.1111/jvim.158411778
DS Docta Complutense
RD 9 abr 2025