RT Journal Article T1 Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials A1 García Fontecha, Ana A1 Cabañas Criado, María Victoria A1 Peña Martínez, Juan A1 Sánchez Salcedo, Sandra AB Advanced bioceramics for bone regeneration constitutes one of the pivotal interest in the multidisciplinar and far-sighted scientific trajectory of Prof. Vallet Regí. The different pathologies that affect osseous tissue substitution are considered to be one of the most important challenges from the health, social and economic point of view. 3D scaffolds based on bioceramics that mimic the composition, environment, microstructure and pore architecture of hard tissues is a consoli16 dated response to such concerns. This review describes not only the different types of materials utilized: from apatites-type to silicon mesoporous materials, but also the fabrication techniques employed to design and adequate microstructure, a hierarchical porosity (from nano to macro scale), a cell-friendly surface; the inclusion of different type of biomolecules, drugs or cells. PB MDPI SN 1999-4923 YR 2021 FD 2021-11-22 LK https://hdl.handle.net/20.500.14352/4998 UL https://hdl.handle.net/20.500.14352/4998 LA eng NO RESEARCH ID B-1301-2015  (Ana García Fontecha)ORCID 0000-0002-8792-872X (Ana García Fontecha)RESEARCH ID G-8740-2015 (María Victoria Cabañas Criado)ORCID 0000-0002-4753-5665 (María Victoria Cabañas Criado)RESEARCH ID N-4501-2014  (Sandra Sánchez Salcedo)ORCID 0000-0002-1889-2057 (Sandra Sánchez Salcedo) NO Unión Europea. Horizonte 2020 NO Ministerio de Ciencia e Innovación (MICINN) NO Instituto de Salud Carlos III (ISCIII)/FEDER DS Docta Complutense RD 7 jun 2025