RT Journal Article
T1 MiSight Assessment Study Spain (MASS). A 2-year randomized clinical trial
A1 Ruiz Pomeda, Alicia
A1 Pérez Sánchez, Belén
A1 Valls Ferran, Isabel
A1 Prieto Garrido, Francisco Luis
A1 Gutiérrez Ortega, Ángel Ramón
A1 Villa Collar, César
AB Purpose: To compare myopia progression in children randomized to MiSight contact lenses (CLs) versus children corrected with single-vision spectacles (SV) over a 2-year period.Methods: Subjects aged 8 to 12 with myopia (−0.75 to −4.00 D sphere) and astigmatism (< −1.00 D cylinder) were assigned to the lens study group (MiSight) or the control group (single vision). Measurements of visual acuity and subjective refraction were taken at 6-month intervals, and axial length, anterior chamber, corneal power, and cycloplegic autorefraction were measured at the baseline, 12-month, and 24-month visits.Results: Eighty-nine subjects were recruited. Forty-fix children were assigned to the MiSight group, and 33 to the single-vision spectacle group. In total, 74 children completed the clinical trial, with the following parameters at the beginning of the study: n = 41 in the MiSight group (age: 11.01 ± 1.23 years, spherical equivalent: −2.16 ± 0.94 D, gender: male: 21, female: 20) and n = 33 in the single-vision group (age: 10.12 ± 1.38 years, spherical equivalent: −1.75 ± 0.94 D, gender: male: 12, female: 21). After 2 years of follow-up, myopia progressed slowly in the MiSight group compared to the control group (0.45 D vs 0.74 D, p < 0.001) and there was less axial elongation in the MiSight group compared to the single-vision group (0.28 mm vs 0.44 mm, p < 0.001). Therefore, use of MiSight CLs produced lower myopia progression (39.32%) and lower axial growth of the eye (36.04%) at 2 years compared to spectacle use.Conclusions: MiSight contact lens wear reduces axial elongation and myopia progression in comparison to distance single-vision spectacles in children.ClinicalTrials.gov Identifier: NCT01917110.
PB Springer
SN 0721-832X
YR 2018
FD 2018-02-03
LK https://hdl.handle.net/20.500.14352/12698
UL https://hdl.handle.net/20.500.14352/12698
LA eng
NO Received: 14 September 2017 ;Revised: 5 December 2017; Accepted: 10 January 2018; Published online: 3 February 2018.
DS Docta Complutense
RD 20 abr 2025