RT Journal Article
T1 Impact of Negative Symptoms on Functioning and Quality of Life in First Psychotic Episodes of Schizophrenia
A1 García Fernández, Lorena
A1 Romero Ferreiro, Verónica
A1 Sánchez Pastor, Luis
A1 Dompablo, Mónica
A1 Martínez Gras, María Isabel
A1 Espejo-Saavedra Roca, Juan Manuel
A1 Rentero, David
A1 Aparicio, Ana Isabel
A1 Álvarez Mon, Miguel Ángel
A1 Lahera, Guillermo
A1 Lee, Jimmy
A1 Santos, Jose Luis
A1 Rodríguez Jiménez, Roberto
AB Negative symptoms are not considered a unitary construct encompassing two different domains, diminished expression, and avolition-apathy. The aim of this study was to explore the relationships between each domain and psychosocial functioning and quality of life in people with a first psychotic episode of schizophrenia. In total, 61 outpatients were assessed with the Clinical Assessment Interview for Negative Symptoms (CAINS), The Functioning Assesment Short Test (FAST) and The Quality of Life Scale (QLS). The mean global score for CAINS was 21.5 (SD: 15.6), with a CAINS Avolition-Apathy (MAP) score of 17.0 (SD: 11.8), and CAINS Diminished Expression (EXP) score of 4.5 (SD: 5.0). The mean FAST score was 31.9 (SD: 18.9), and 41.1 (SD: 17.9) for QLS. Linear regression analysis revealed a significant (F(4,53) = 15.65, p < 0.001) relationship between MAP and EXP CAINS’ score and FAST score. CAINS-MAP was more predictive of FAST scores (β = 0.44, p = 0.001) than CAINS-EXP (β = 0.37, p = 0.007). Linear regression analysis for QLS revealed a significant model (F(4,56) = 29.29, p < 0.001). The standardized regression weight for the CAINS-MAP was around three times greater (β = −0.63, p < 0.001) than for CAINS-EXP (β = −0.24, p = 0.024). The two different domains are associated differently with functionality and quality of life.
PB MPDI
SN 2077-0383
YR 2022
FD 2022-02-14
LK https://hdl.handle.net/20.500.14352/71633
UL https://hdl.handle.net/20.500.14352/71633
LA eng
NO Instituto de Salud Carlos III (ISCIII)/ FEDER
NO Comunidad de Madrid/FEDER
DS Docta Complutense
RD 10 abr 2025