RT Journal Article
T1 Clinical and hemodynamic results after direct transcatheter aortic valve replacement versus pre-implantation balloon aortic valvuloplasty: A case-matched analysis
A1 Ferrera, Carlos
A1 Viana Tejedor, Ana Teresa
A1 De Agustín Loeches, José Alberto
A1 Pérez De Isla, Leopoldo
A1 Fernández Pérez, Cristina
A1 Escaned Barbosa, Javier
A1 Fernández Ortiz, Antonio Ignacio
A1 Macaya Miguel, Carlos
AB ObjectivesTo evaluate the safety and midterm hemodynamic results of direct transcatheter aortic valve replacement (TAVR) without pre-implantation balloon aortic valvuloplasty (BAV).BackgroundBAV was considered a mandatory previous step in TAVR procedures.MethodsA total of 339 consecutive patients who underwent transfemoral TAVR were prospectively selected. A 1:1 matching was conducted, pairing age, prosthesis type (self-expandable or balloon expandable) and size, and valve calcification grade (48% with moderate to severe valve calcification). Finally, 102 pairs (102 patients with previous BAV and 102 without BAV) were obtained.ResultsDirect TAVR was feasible in all patients without any crossover to BAV group. Device success was achieved in 91.2% and 90.2% of cases in direct TAVR and pre-BAV groups (P = 0.810), respectively, without any differences in balloon postdilation rate and residual aortic regurgitation. The amount of contrast agent, acute kidney injury and myocardial injury was significantly lower in the direct implantation group (P < 0.05). No differences were found in 30-day and 1-year mortality between both groups (4.9% vs. 9.8%, P = 0.177 and 14.0% vs. 23.8%, P = 0.771, respectively). Hemodynamic parameters remained stable after 1-year follow-up in both groups.ConclusionsDirect transfemoral TAVR without prior BAV was safe in patients with calcified severe aortic stenosis. Pre-implantation BAV could be omitted in patients undergoing TAVR, without influence in procedure success rate, and subsequent patients' clinical course and valve hemodynamic performance. © 2016 Wiley Periodicals, Inc.
PB Wiley
SN 1522-1946
YR 2017
FD 2017-11-06
LK https://hdl.handle.net/20.500.14352/131320
UL https://hdl.handle.net/20.500.14352/131320
LA eng
NO Ferrera, C., Nombela-Franco, L., Garcia, E., Jimenez-Quevedo, P., Biagioni, C., Gonzalo, N., Nuñez-Gil, I., Viana-Tejedor, A., Salinas, P., Alberto de Agustin, J., Almeria, C., Islas, F., Perez de Isla, L., Fernandez-Perez, C., Escaned, J., Fernández-Ortiz, A., & Macaya, C. (2017). Clinical and hemodynamic results after direct transcatheter aortic valve replacement versus pre-implantation balloon aortic valvuloplasty: A case-matched analysis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 90(5), 809–816. https://doi.org/10.1002/ccd.26671
DS Docta Complutense
RD 26 feb 2026