TY - JOUR AU - Sánchez Sánchez, Roberto AU - Ferré Pérez, Ignacio AU - Re, Michela Tatiana AU - Ramos, Juan José AU - Regidor Cerrillo, Javier AU - Pizarro Díaz, Manuel AU - González Huecas, Marta AU - Tabanera De Lucio, Enrique AU - Benavides, Julio AU - Hemphill, Andrew AU - Hulverson, Matthew A. AU - Barrett, Lynn K. AU - Choi, Ryan AU - Whitman, Grant R. AU - Ojo, Kayode K. AU - Van Voorhis, Wesley C. AU - Ortega Mora, Luis Miguel PY - 2019 DO - 10.1128/AAC.02527-18 SN - 0066-4804 UR - https://hdl.handle.net/20.500.14352/112160 T2 - Antimicrobial Agents and Chemotherapy AB - Previous studies on drug efficacy showed low protection against abortion and vertical transmission of Toxoplasma gondii in pregnant sheep. Bumped kinase inhibitors (BKIs), which are ATP-competitive inhibitors of calcium-dependent protein kinase 1... LA - eng M2 - 1 PB - ASM Journals KW - BKI-1294 KW - Toxoplasma gondii KW - Abortion KW - Protein kinase inhibitor KW - Safety KW - Sheep KW - Treatment KW - Vertical transmission TI - Treatment with Bumped Kinase Inhibitor 1294 Is Safe and Leads to Significant Protection against Abortion and Vertical Transmission in Sheep Experimentally Infected with Toxoplasma gondii during Pregnancy TY - journal article VL - 63 ER -