RT Journal Article T1 Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela A1 Delgado Blas, José Francisco A1 Martínez Ovejero, Cristina A1 Abadia Patiño, Lorena A1 González Zorn, Bruno AB We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal, and environmental Enterobacteriaceae samples from Cumana, Venezuela, that were collected in 2015. The mcr-1 gene was detected in 2/93 Escherichia coli isolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes. PB American Society for Microbiology SN 0066-4804 YR 2016 FD 2016-10 LK https://hdl.handle.net/20.500.14352/18986 UL https://hdl.handle.net/20.500.14352/18986 LA eng NO Unión Europea. FP7 NO Ministerio de Economía y Competitividad (MINECO) DS Docta Complutense RD 7 abr 2025