RT Journal Article
T1 Investigating the Role of Insight, Decision-Making and Mentalizing in Functional Outcome in Schizophrenia: A Cross-Sectional Study
A1 Escobedo Aedo, Paula Jhoana
A1 Forjan González, Ana
A1 Sánchez Escribano Martínez, Adela
A1 Ruiz Ruano, Verónica González
A1 Sánchez Alonso, Sergio
A1 Mata Iturralde, Laura
A1 Muñoz Lorenzo, Laura
A1 Baca García, Enrique
A1 David, Anthony S.
A1 Lopez Morinigo, Javier-David
AB Background: Recovery has become a priority in schizophrenia spectrum disorders (SSDs). This study aimed to investigate predictors of objective—general functioning and disability—and subjective—quality of life (QoL)—measures of functional outcomes in SSD.Methods: Sample: n = 77 SSD outpatients (age 18–64, IQ > 70) participating in a randomised controlled trial. Baseline data were used to build three multivariable linear regression models on: (i) general functioning—General Assessment of Functioning (GAF); (ii) disability—the World Health Organization Disability Assessment Schedule (WHODAS-2.0); and (iii) QoL—Satisfaction Life Domains Scale (SLDS).Results: Young age and being employed (R2 change = 0.211; p = 0.001), late adolescence premorbid adjustment (R2 change = 0.049; p = 0.0050), negative symptoms and disorganization (R2 change = 0.087; p = 0.025) and Theory of Mind (R2 change = 0.066, p = 0.053) predicted general functioning. Previous suicidal behaviour (R2 change = 0.068; p = 0.023) and negative and depressive symptoms (R2 change = 0.167; p = 0.001) were linked with disability. Previous suicidal behaviour (R2 change = 0.070, p = 0.026), depressive symptoms (R2 change = 0.157; p < 0.001) and illness recognition (R2 change = 0.046, p = 0.044) predicted QoL.Conclusions: Negative, disorganization and depressive symptoms, older age, unemployment, poor premorbid adjustment, previous suicide attempts and illness awareness appear to underlie a poor global functional outcome in SSD. Achieving recovery in SSD appears to require both symptomatic remission (e.g., through antipsychotics) and measures to improve mastery and relieve low mood.
PB MPDI
SN 2076-328X
YR 2022
FD 2022-01-27
LK https://hdl.handle.net/20.500.14352/71748
UL https://hdl.handle.net/20.500.14352/71748
LA eng
NO Unión Europea. Horizonte 2020
DS Docta Complutense
RD 21 sept 2024