RT Journal Article
T1 Obsessive–compulsive and catatonic symptoms in the early stages of psychosis: Are they related?
A1 Sánchez Alonso, Sergio
A1 Canal-Rivero, Manuel
A1 Garrido-Torres, Nathalia
A1 Baca-Garcia, Enrique
A1 Crespo-Facorro, Benedicto
A1 Barrigón Estévez, María Luisa
A1 Ruiz-Veguilla, Miguel
AB Objective: Catatonia and obsessive–compulsive symptoms (OCS) are frequently observed in patients with psychosis, even at early stages, yet their relationship remains unclear. This study aimed to examine the prevalence and association of catatonic symptoms and OCS in early-stage psychosis. Methods: Seventy patients aged 18–55 years with early-stage psychosis (illness duration < 5 years) were assessed within 72 h of admission. Catatonic symptoms were evaluated using the Bush Francis Catatonia Rating Scale (BFCRS), OCS with the Obsessive–Compulsive Inventory-Revised (OCI-R), and psychotic symptoms with the Positive and Negative Syndrome Scale (PANSS). Correlations between catatonic, obsessive–compulsive, and psychotic symptom dimensions were analyzed. Logistic regression assessed associations between symptom dimensions and catatonia. Results: Catatonic symptoms (BFCRS ≥ 3) were present in 64.3% of patients, and 40% scored above the OCI-R cut-off for clinically significant OCS. Patients with catatonia had significantly higher total OCI-R scores and higher scores across all OCI-R subscales. Strong correlations were observed between mental neutralization and washing OCI-R subscales and BFCRS scores. Logistic regression showed that higher disorganized (OR = 1.699, 95% CI: 1.141–2.529, p = 0.009) and obsessive–compulsive symptoms (OR = 1.253, 95% CI: 1.058–1.483, p = 0.009) were independently associated with increased odds of catatonia, while positive symptoms showed a significant negative association (OR = 0.796, 95% CI: 0.644–0.983, p = 0.034). Conclusions: There is a high prevalence of both catatonic and obsessive–compulsive symptoms in early-stage psychosis. Disorganized and obsessive–compulsive symptoms are independent risk factors for catatonia, while positive symptoms may be protective. These findings highlight the importance of comprehensive symptom assessment in this population.
PB SPRINGER NATURE
SN 0940-1334
SN 1433-8491
YR 2025
FD 2025
LK https://hdl.handle.net/20.500.14352/133036
UL https://hdl.handle.net/20.500.14352/133036
LA eng
NO Sanchez-Alonso, S., Canal-Rivero, M., Garrido-Torres, N., Baca-Garcia, E., Crespo-Facorro, B., Barrigon, M. L., & Ruiz-Veguilla, M. (2025). Obsessive-compulsive and catatonic symptoms in the early stages of psychosis: Are they related?. European archives of psychiatry and clinical neuroscience, 275(8), 2523–2533. https://doi.org/10.1007/s00406-025-02080-2
NO 2025 Acuerdos transformativos CRUE
NO Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Partially funded by Research project of excellence with ref. ProyExcel_00658, call 2021, of grants for entities qualified as agents of the Andalusian Knowledge System, within the scope of the Andalusian Plan for Research, Development and Innovation (PAIDI 2020) of the Ministry of Economic Transformation, Industry, Knowledge and Universities.
DS Docta Complutense
RD 24 abr 2026