RT Journal Article T1 Exploring the hidden complexity: entropy analysis in pulse oximetry of female athletes A1 Cabanas, Ana M A1 Fuentes-Guajardo, Macarena A1 Sáez, Nicolás A1 Catalán, Davidson A1 Collao-Caiconte, Patricio O. A1 Martín Escudero, María Del Pilar AB This study examines the relationship between physiological complexity, as measured by Approximate Entropy (ApEn) and Sample Entropy (SampEn), and fitness levels in female athletes. Our focus is on their association with maximal oxygen consumption (𝑉𝑂2,𝑚𝑎𝑥). Our findings reveal a complex relationship between entropy metrics and fitness levels, indicating that higher fitness typically, though not invariably, correlates with greater entropy in physiological time series data; however, this is not consistent for all individuals. For Heart Rate (HR), entropy measures suggest stable patterns across fitness categories, while pulse oximetry (𝑆𝑝𝑂2) data shows greater variability. For instance, the medium fitness group displayed an ApEn(HR) = 0.57±0.13 with a coefficient of variation (CV) of 22.17 and ApEn(𝑆𝑝𝑂2) = 0.96±0.49 with a CV of 46.08%, compared to the excellent fitness group with ApEn(HR) = 0.60±0.09 with a CV of 15.19% and ApEn(𝑆𝑝𝑂2) =0.85±0.42 with a CV of 49.46%, suggesting broader physiological responses among more fit individuals. The larger standard deviations and CVs for 𝑆𝑝𝑂2 entropy may indicate the body’s proficient oxygen utilization at higher levels of physical demand. Our findings advocate for combining entropy metrics with wearable sensor technology for improved biomedical analysis and personalized healthcare. PB MDPI SN 2079-6374 YR 2024 FD 2024 LK https://hdl.handle.net/20.500.14352/105957 UL https://hdl.handle.net/20.500.14352/105957 LA eng NO Biosensors 2024, 14(1), 52; https://doi.org/10.3390/bios14010052 NO ANID NO MINEDUC DS Docta Complutense RD 21 abr 2025