RT Journal Article
T1 Factors Associated with the Presence of Nonalcoholic Steatohepatitis in Patients with Chronic Hepatitis C
A1 Solís Herruzo, José Antonio
A1 Pérez Carreras, Mercedes
A1 Rivas, Eloy
A1 Fernández Vázquez, María Inmaculada
A1 Garfia Castillo, María Cristina
A1 Bernardos, Esther
A1 Castellano Tortajada, Gregorio
A1 Colina Ruiz-Delgado, Francisco
AB ORIGINAL CONTRIBUTIONS: LIVER AND BILIARFactors Associated with the Presence of Nonalcoholic Steatohepatitis in Patients with Chronic Hepatitis CSolis-Herruzo, José A.; Pérez-Carreras, Mercedes; Rivas, Eloy; Fernández-Vázquez, Inmaculada; Garfia, Cristina; Bernardos, Esther; Castellano, Gregorio; Colina, FranciscoAuthor InformationAmerican Journal of Gastroenterology 100(5):p 1091-1098, May 2005.BuyAbstractOBJECTIVES The aim of this study was to identify factors associated with the presence of nonalcoholic steatohepatitis (NASH) in patients with chronic hepatitis C (CHC).METHODS We studied 98 patients with CHC [47 with NASH (group HCV/NASH), 51 without NASH (group HCV)] and 85 with NASH not infected with hepatitis C virus (HCV) (group NASH). We determined factors associated with the presence of NASH in patients with hepatitis C.RESULTS Group HCV/NASH patients resembled those with NASH. Body mass index (BMI) was higher in group HCV/NASH than in group HCV, but was similar to group NASH. Most HCV/NASH patients had risk factors for NASH. In patients infected with HCV, NASH and NASH-related lesions were independently associated with BMI, while steatosis score was associated with HCV genotype 3 and BMI. Fibrosis stage was independently associated with steatosis, necroinflammatory activity index, and NASH lesions.CONCLUSION While HCV genotype 3 infection and BMI are associated with the presence of steatosis in CHC, BMI is the only factor independently associated with the presence of NASH in these patients. We suggest that overweight-related factors might induce NASH in CHC patients.
PB Wolters Kluwer
SN 0002-9270
YR 2005
FD 2005-05
LK https://hdl.handle.net/20.500.14352/113890
UL https://hdl.handle.net/20.500.14352/113890
LA eng
NO Solis-Herruzo, José A.; Pérez-Carreras, Mercedes; Rivas, Eloy; Fernández-Vázquez, Inmaculada; Garfia, Cristina; Bernardos, Esther; Castellano, Gregorio; Colina, Francisco. Factors Associated with the Presence of Nonalcoholic Steatohepatitis in Patients with Chronic Hepatitis C. American Journal of Gastroenterology 100(5):p 1091-1098, May 2005.
NO Instituto de Salud Carlos III (España)
DS Docta Complutense
RD 17 abr 2025