RT Journal Article
T1 Molecular Imaging in Ischemic Heart Disease
A1 Lavín Plaza, Begoña
A1 Theodoulou, Iakovos
A1 Rashid, Imran
A1 Hajhosseiny, Reza
A1 Phinikaridou, Alkystis
A1 Botnar, Rene
AB This review summarizes the state of art of non-invasive molecular imaging of the myocardium during ischemia and after myocardial infarction using PET and MRI. We also describe the different contrast agents that have been developed to image the different phases of cardiac healing and the biological processes associated with each of those phases. Importantly, here we focus on imaging of inflammation as it is the key biological process that orchestrates clearance of dead cells, tissue remodeling, cardiac repair, and future outcome. We also focus on clinical translation of some of the novel contrast agents that have been tested in patients and discuss the need for larger, multi-center patient studies to fully validate the applicability of new imaging probes.
PB Springer
SN 1941-9066
YR 2019
FD 2019
LK https://hdl.handle.net/20.500.14352/98673
UL https://hdl.handle.net/20.500.14352/98673
LA eng
NO Lavin Plaza, Begoña, et al. «Molecular Imaging in Ischemic Heart Disease». Current Cardiovascular Imaging Reports, vol. 12, n.o 7, julio de 2019, p. 31. https://doi.org/10.1007/s12410-019-9500-x.
NO Wellcome Trust
NO British Heart Foundation
NO Engineering & Physical Sciences Research Council (Reino Unido)
DS Docta Complutense
RD 17 mar 2026