RT Journal Article T1 Association between Mineral Intake and Cognition Evaluated by Montreal Cognitive Assessment (MoCA): A Cross-Sectional Study A1 Lorenzo-Mora, Ana M. A1 López Sobaler, Ana María A1 Bermejo López, Laura María A1 González Rodríguez, Liliana Guadalupe A1 Cuadrado Soto, Esther A1 Peral Suárez, África A1 Salas González, María Dolores A1 Delgado Losada, María Luisa A1 Rodríguez Rojo, Inmaculada Concepción A1 Barabash Bustelo, Ana A1 Maestu Unturbe, Fernando A1 Aparicio Vizuete, Aranzazu AB Background: Mineral intake may protect against cognitive impairment (CI) and all-cause dementia, which affects a large number of adults worldwide. The aim of this study was to investigate the association between mineral intake and Montreal Cognitive Assessment (MoCA), which is a sensitive and specific test. Methods: In total, 201 adults were included in a cross-sectional study. They completed a three-day dietary record to estimate their average daily intake of minerals. Contributions to dietary reference intakes (DRIs) were also calculated. The participants were divided into tertiles according to their mineral intake. CI classifications were determined via the MoCA (score < 26). Apolipoprotein E (APOE) genotyping was carried out, and the patients’ anthropometric measurements and physical activity, health and personal data were collected. Results: The prevalence of CI in this selective sample was 54.2% (34.3% females and 19.9% males). In women, being in the third tertiles of iron and manganese intake was associated with lower odds of having CI (OR [95% CI]: 0.32 [0.11 ± 0.93]; 0.33 [0.12 ± 0.93], p < 0.05). No significant differences were observed for any of the nutrients studied in men. Conclusions: These findings suggest that a low mineral intake, especially low iron and manganese intake in women, is associated with a worse cognition as assessed by MoCA. PB MDPI YR 2023 FD 2023-10-24 LK https://hdl.handle.net/20.500.14352/103715 UL https://hdl.handle.net/20.500.14352/103715 LA eng NO Lorenzo-Mora, A. M., López-Sobaler, A. M., Bermejo, L. M., González-Rodríguez, L. G., Cuadrado-Soto, E., Peral-Suárez, Á., Salas-González, M. D., Delgado-Losada, M. L., Rodríguez-Rojo, I. C., Barabash, A., Maestú-Unturbe, F., & Aparicio, A. (2023). Association between Mineral Intake and Cognition Evaluated by Montreal Cognitive Assessment (MoCA): A Cross-Sectional Study. Nutrients, 15(21), 4505. https://doi.org/10.3390/nu15214505 NO Ministerio de Economía, Comercio y Empresa (España) NO Universidad Complutense de Madrid NO Ministerio de Ciencia, Innovación y Universidades (España) NO Banco Santander NO European Commission DS Docta Complutense RD 10 abr 2025