RT Journal Article
T1 Biological performance of hydroxyapatite-biopolymer foams: in vitro cell response
A1 Cicuéndez Maroto, Mónica
A1 Izquierdo Barba, Isabel
A1 Vila Juárez, Mercedes
A1 Sánchez Salcedo, Sandra
A1 Vallet Regí, María Dulce Nombre
AB Uncoated and biopolymer-coated nanocrystalline hydroxyapatite (HA) macroporous foams are presented as promising candidates as scaffolds for bone tissue regeneration. To this end, foam degradability, the cytotoxic effects on osteoblast-like cells of foam degradation by-products and biocompatibility with osteoblast-like cells were assayed on the three-dimensional (3-D) foam surface. The results show that the 3-D interconnected architectural design of these HA foams allows excellent osteoblast internalization, proliferation and differentiation, exhibiting adequate colonization over the entire scaffold surface with an appropriate degradation rate without any cytotoxic effects.
PB Elsevier
YR 2012
FD 2012
LK https://hdl.handle.net/20.500.14352/96640
UL https://hdl.handle.net/20.500.14352/96640
LA eng
NO Biological performance of hydroxyapatite-biopolymer foams: In vitro cell response. Acta Biomaterialia, Vol. 8, Núm. 2, 2012, pp. 802-810. DOI:10.1016/J.ACTBIO.2011.09.019
NO Ministerio de Ciencia y Tecnología(España)
NO Comunidad de Madrid
DS Docta Complutense
RD 7 abr 2025