RT Journal Article
T1 Transcatheter Mitral Repair for Functional Mitral Regurgitation According to Left Ventricular Function: A Real-Life Propensity-Score Matched Study
A1 Pascual, Isaac
A1 Nombela-Franco, Luis
A1 Jimenez-Quevedo, Pilar
A1 De Agustín Loeches, José Alberto
A1 Tirado-Conte, Gabriela
A1 Estevez-Loureiro, Rodrigo
AB Background: Transcatheter mitral valve repair (TMVR) could improve survival in functional mitral regurgitation (FMR), but it is necessary to consider the influence of left ventricular ejection fraction (LVEF). Therefore, we compare the outcomes after TMVR with Mitraclip® between two groups according to LVEF. Methods: In an observational registry study, we compared the outcomes in patients with FMR who underwent TMVR with and without LVEF <30%. The primary endpoint was the combined one-year all-cause mortality and unplanned hospital readmissions due to HF. The secondary end-points were New York Heart Association (NYHA) functional class and mitral regurgitation (MR) severity. Propensity-score matching was used to create two groups with the same baseline characteristics, except for baseline LVEF. Results: Among 535 FMR eligible patients, 144 patients with LVEF <30% (group 1) and 144 with LVEF >30% (group 2) had similar propensity scores and were included in the analyses. The primary study endpoint was significantlly higher in group 1 (33.3% vs. 9.4%, p = 0.002). There was a maintained improvement in secondary endpoints without significant differences among groups. Conclusion: FMR patients with LVEF <30% treated with MitraClip® had higher mortality and readmissions than patients with LVEF ≥30% treated with the same device. However, both groups improved the NYHA functional class and MR severity.
PB MDPI
SN 2077-0383
YR 2020
FD 2020
LK https://hdl.handle.net/20.500.14352/131114
UL https://hdl.handle.net/20.500.14352/131114
LA eng
NO Pascual, I., Carrasco-Chinchilla, F., Benito-Gonzalez, T., Li, C. H., Avanzas, P., Nombela-Franco, L., Pan, M., Serrador Frutos, A., Freixa, X., Trillo-Nouche, R., Hernández-Antolín, R. A., Andraka Ikazuriaga, L., Cruz-Gonzalez, I., López-Mínguez, J. R., Diez, J. L., Berenguer-Jofresa, A., Sanchis, J., Ruiz-Quevedo, V., Urbano-Carrillo, C., Dominguez, J. F. O., … Estevez-Loureiro, R. (2020). Transcatheter Mitral Repair for Functional Mitral Regurgitation According to Left Ventricular Function: A Real-Life Propensity-Score Matched Study. Journal of clinical medicine, 9(6), 1792. https://doi.org/10.3390/jcm9061792
DS Docta Complutense
RD 22 mar 2026