RT Journal Article T1 Trends in asthma hospitalizations among adults in Spain: Analysis of hospital discharge data from 2011 to 2020 A1 Caballlero Segura, Francisco A1 López de Andrés, Ana A1 Jiménez García, Rodrigo A1 Miguel Yanes, José María de A1 Hernández Barrera, Valentín A1 Carabantes Alarcón, David A1 Zamorano León, José Javier A1 Miguel Díez, Javier de AB Aims: To analyze trends in asthma hospitalizations in patients over 15 years of age in Spain. To identify possible changes in incidence, demographic characteristics, clinical conditions, and outcomes. Methods: We conducted an observational retrospective epidemiological study using the Spanish National Hospital Discharge Database and included all patients hospitalized with a diagnosis of asthma from 2011 to 2020. Results: A total of 1,102,923 patients were hospitalized with a code for asthma in any diagnostic position; of these, 153,749 (13.94%) had asthma coded as the primary diagnosis (asthma exacerbation). The number of patients with an asthma exacerbation decreased over time, from 15,356 in 2011 to 8804 in 2020. In-hospital mortality (IHM) remained low (around 1.5%) and stable in this subgroup of patients. When the diagnosis of asthma appeared in any diagnostic position, hospitalizations increased for all ages and sexes. In this case, a significant change was observed for IHM, which increased from 3.27% in 2011–12 to 4.36% in 2019–20 (p < 0.001). The main risk factors for IHM in both cases were age over 65 years, need for mechanical ventilation, and associated diagnoses of pneumonia, heart disease, or atrial fibrillation. In contrast, obesity was a predictor of lower mortality.Conclusion: Our results suggest a decline in the incidence of hospitalizations for asthma exacerbations from 2011 to 2020. In contrast, the number of patients with asthma in any diagnostic position increased progressively, as did mortality, probably owing to an increase in comorbidities in a gradually ageing population. PB Elsevier YR 2022 FD 2022-10-12 LK https://hdl.handle.net/20.500.14352/72535 UL https://hdl.handle.net/20.500.14352/72535 LA eng NO CRUE-CSIC (Acuerdos Transformativos 2022) NO Universidad Complutense de Madrid/Comunidad de Madrid NO Universidad Complutense de Madrid DS Docta Complutense RD 27 jul 2024