RT Journal Article T1 β-Lactam resistance in Haemophilus parasuis is mediated by plasmid pB1000 bearing blaROB-1 A1 San Millán, Álvaro A1 Escudero García-Calderón, José Antonio A1 Catalán, Ana A1 Nieto, Silvia A1 Farelo, Fidel A1 Gibert, Magdalena A1 Moreno Romo, Miguel Ángel A1 Domínguez Rodríguez, Lucas José A1 González Zorn, Bruno AB beta-Lactam resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. Clinical high-level beta-lactam-resistant isolates from Spain bore a novel plasmid, pB1000, expressing a functionally active ROB-1 beta-lactamase. Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000. PB American Society for Microbiology SN 0066-4804 YR 2007 FD 2007 LK https://hdl.handle.net/20.500.14352/94208 UL https://hdl.handle.net/20.500.14352/94208 LA eng NO San Millan, A., Escudero, J. A., Catalan, A., Nieto, S., Farelo, F., Gibert, M., Moreno, M. A., Dominguez, L., & Gonzalez-Zorn, B. (2007). Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1. Antimicrobial agents and chemotherapy, 51(6), 2260–2264. https://doi.org/10.1128/AAC.00242-07 NO Ministerio de Educación y Ciencia (España) NO Universidad Complutense de Madrid NO Comunidad de Madrid DS Docta Complutense RD 9 abr 2025