RT Journal Article T1 Digital Surgical Guides in Bone Regeneration: Literature Review and Clinical Case Report A1 Iglesias Velázquez, Óscar A1 Xin Gao, Baoluo A1 González Fernández-Tresguerres, Francisco A1 Saez Alcaide, Luis Miguel A1 Leco Berrocal, María Isabel A1 Torres García Denche, Jesús AB The present study describes a digitally guided workflow for the Split Bone Block Technique (SBBT) using standardized cortical and particulate allogeneic grafts in combination with custom-designed, 3D-printed surgical guides. The aim was to illustrate the feasibility of a donor-site-free alternative to the conventional autologous approach, which remains technically demanding and associated with increased morbidity. A narrative literature review and a single clinical case report were conducted to contextualize the proposed workflow. Digital planning was performed by merging DICOM and STL datasets to design cutting boxes for standardized allogeneic laminae and a transporter guide for intraoperative positioning. The technique was applied in a patient with severe horizontal ridge atrophy. Primary wound closure and uneventful healing were achieved. Six-month CBCT evaluation demonstrated an increase in horizontal ridge width from 2 mm to 8 mm. Within the limitations of a single illustrative case, this report suggests that a fully guided allogeneic SBBT workflow is feasible and may facilitate controlled graft adaptation while avoiding autologous bone harvesting. Further controlled clinical studies are required to evaluate accuracy, reproducibility, and long-term outcomes. PB MDPI SN 2076-3417 YR 2026 FD 2026-01-05 LK https://hdl.handle.net/20.500.14352/131289 UL https://hdl.handle.net/20.500.14352/131289 LA eng NO Iglesias-Velázquez Ó, Xing Gao B, Tresguerres FGF, Sáez Alcaide LM, Leco Berrocal I, Torres García-Denche J. Digital Surgical Guides in Bone Regeneration: Literature Review and Clinical Case Report. Applied Sciences. 2026; 16(1):537. https://doi.org/10.3390/app16010537 DS Docta Complutense RD 25 mar 2026