TY - JOUR AU - Abuin Martínez, Cristina AU - Vidal Casado, Rebeca AU - Gutiérrez López, María Dolores AU - Pérez Hernández, Mercedes AU - O'Shea Gaya, María Esther AU - Giménez Gómez, Pablo AU - Morales Puerto, Nuria AU - O'Shea Gaya, María Esther AU - Colado Megías, María Isabel PY - 2021 DO - 10.1016/j.neuropharm.2021.108490 SN - 0028-3908 UR - https://hdl.handle.net/20.500.14352/112141 T2 - Neuropharmacology AB - 3,4-Methylenedioxymethamphetamine (MDMA) is an amphetamine derivative that has been shown to produce serotonergic damage in the brains of primates, including humans, and of rats. Tryptophan, the precursor of serotonin, is primarily degraded through... LA - eng M2 - 1 PB - Elsevier KW - MDMA KW - Kynurenine KW - Tryptophan KW - 2,3-dioxygenase KW - Aryl hydrocarbon receptors KW - Neurotoxicity KW - 3,3′-Diindolylmethane TI - Increased kynurenine concentration attenuates serotonergic neurotoxicity induced by 3,4-methylenedioxymethamphetamine (MDMA) in rats through activation of aryl hydrocarbon receptor TY - journal article VL - 187 ER -