RT Journal Article T1 Electrochemical (bio)sensors based on covalent organic frameworks (COFs) T2 (Bio)sensores electroquímicos basados en marcos orgánicos covalentes (COF) A1 Martínez-Periñán, Emiliano A1 Martínez-Fernández, Marcos A1 Segura Castedo, José Luis A1 Lorenzo, Encarnación AB Covalent organic frameworks (COFs) are defined as crystalline organic polymers with programmable topological architectures using properly predesigned building blocks precursors. Since the development of the first COF in 2005, many works are emerging using this kind of material for different applications, such as the development of electrochemical sensors and biosensors. COF shows superb characteristics, such as tuneable pore size and structure, permanent porosity, high surface area, thermal stability, and low density. Apart from these special properties, COF’s electrochemical behaviour can be modulated using electroactive building blocks. Furthermore, the great variety of functional groups that can be inserted in their structures makes them interesting materials to be conjugated with biological recognition elements, such as antibodies, enzymes, DNA probe, aptamer, etc. Moreover, the possibility of linking them with other special nanomaterials opens a wide range of possibilities to develop new electrochemical sensors and biosensors. SN 1424-8220 YR 2022 FD 2022 LK https://hdl.handle.net/20.500.14352/100424 UL https://hdl.handle.net/20.500.14352/100424 LA eng NO Martínez-Periñán, E.; Martínez-Fernández, M.; Segura, J.L.; Lorenzo, E. Electrochemical (Bio)Sensors Based on Covalent Organic Frameworks (COFs). Sensors 2022, 22, 4758. https://doi.org/10.3390/s22134758 NO Ministerio de Ciencia e Innovación (España) NO Ministerio de Economía y Competitividad (España) NO Comunidad de Madrid DS Docta Complutense RD 6 abr 2025