RT Journal Article
T1 Influence of baseline demographic and clinical characteristics in the visual outcome of intermediate uveitis: a survival analysis
A1 Abásolo Alcázar, Lydia
A1 Prieto García, Ángela
A1 Díaz Valle, David
A1 Benítez Del Castillo Sánchez, José Manuel
A1 Pato, Esperanza
A1 García Feijoo, Julián
A1 Fernández Gutiérrez, Benjamín
A1 Rodríguez Rodríguez, Luis
AB Background/aims To describe in patients diagnosed with intermediate uveitis (IU) the incidence rate (IR) of visual loss and newly diagnosed clinical complications during follow-up. Also, to analyse the influence of baseline complications on visual loss.Methods Longitudinal retrospective cohort study which included 97 affected eyes of 67 consecutive patients diagnosed with IU according to the Standardization of Uveitis Nomenclature group, first seen in our clinic between 1986 and 2014, and until loss to follow-up, or 1 January 2015. Kaplan–Meier curves were set to account for temporary and permanent visual loss and development of clinical complications during follow-up. Cox's bivariate and multivariate regression models were constructed to examine the risk factors for visual loss.Results IRs (in events per 100 eyes-year) for the development of cystic macular oedema (CMO), epiretinal membrane (ERM) and cataracts were 5.9 (3.70–9.4), 1.2 (0.50–2.6) and 6.6 (4.4–10.1), respectively. IRs per 100 eyes-year of temporary moderate and severe visual loss episodes were 43.8 (37.3–51.4) and 6.4 (4.5–9.0), respectively. IR of permanent moderate visual loss was 5.3 (3.3–8.3). After 2 years of follow-up, 21% of eyes had developed a permanent moderate visual loss. Presence at baseline of lower visual acuity was associated with higher IR of temporary visual loss episodes, and CMO was associated with higher IR of temporary moderate visual loss.Conclusions IU seems to have a favourable long-term prognosis. Permanent visual loss occurs during the first year of the disease. Baseline characteristics could identify patients with a higher risk of poor visual prognosis.
PB BMJ Publishing Group
SN 0007-1161
YR 2016
FD 2016-03-30
LK https://hdl.handle.net/20.500.14352/112386
UL https://hdl.handle.net/20.500.14352/112386
LA eng
NO Abásolo L, Prieto-García Á, Díaz-Valle D, et alInfluence of baseline demographic and clinical characteristics in the visual outcome of intermediate uveitis: a survival analysisBritish Journal of Ophthalmology 2016;100:1651-1655.
DS Docta Complutense
RD 10 abr 2025