RT Conference Proceedings T1 Geometry Induced Biofilm Formation A1 Carpio Rodríguez, Ana María A1 Espeso, David R. AB Bacteria in aqueous environments usually gather to form aggregates called biofilms. In biofilms, cells display many behavioral differences from planktonic cells, such as a 1,000-fold increase in tolerance to antibiotics. Hospital-acquired infections are often caused by biofilm spread through medical systems. Design improvements hindering biofilm formation rely on identifying factors that favor their appearance. Geometry variations in medical flow circuits may trigger biofilm nucleation through vortical motion driving bacteria to walls. Detailed flow studies in mili and microfluidic devices support that observation. Once biofilm seeds are created, they proliferate forming filaments whose structure is again controlled by the geometry. YR 2015 FD 2015 LK https://hdl.handle.net/20.500.14352/36156 UL https://hdl.handle.net/20.500.14352/36156 LA eng NO Ministerio de Ciencia, Innovación y Universidades (España) DS Docta Complutense RD 21 abr 2025