RT Journal Article T1 Phenolic metabolites in plasma and thigh meat of chickens supplemented with grape byproducts A1 Muñoz González, Irene A1 Chamorro Francisco, Susana A1 Pérez Jiménez, Jara A1 López Andrés, Patricia A1 Álvarez Acero, Inmaculada A1 Herrero Herranz, Ana María A1 Nardoia, Marı́a A1 Brenes, Agustín A1 Viveros Montoro, Agustín A1 Arija Martín, Ignacio A1 Rey Muñoz, Ana Isabel A1 Ruiz Capillas, Claudia AB Grape byproducts are rich sources of polyphenols with powerful antioxidant and health-promoting effects. The impact of supplementing chicken diets with grape byproducts on plasma and thigh meat concentrations of phenolic metabolites was evaluated by analyzing samples by high-performance liquid chromatography quadrupole time of flight mass spectrometry. Chickens were fed three experimental diets: Control diet, Control+8% grape pomace, and Control+0.1% grape seed extract. In plasma, 32 phenolic metabolites were identified, some of which were conjugated catechin/epicatechin metabolites exclusively identified in chickens fed diets enriched in grape byproducts. Also, these chickens showed significantly higher plasmatic concentrations of 21 phenolic metabolites. In thigh meat, 14 phenolic metabolites were identified, but no differences were found between diets. Higher plasmatic tocopherol was found when supplementing diets with grape byproducts, while no changes were observed in meat. Thus, supplementing chicken diets with grape byproducts leads to a significant increase in the circulation of phenolic metabolites and tocopherol. PB American Chemical Society SN 0021-8561 SN 1520-5118 YR 2019 FD 2019-04 LK https://hdl.handle.net/20.500.14352/109818 UL https://hdl.handle.net/20.500.14352/109818 LA eng NO Muñoz-González I, Chamorro S, Pérez-Jiménez J, López-Andrés P, Álvarez-Acero I, Herrero AM, Nardoia M, Brenes A, Viveros A, Arija I, Rey A, Ruiz-Capillas C. Phenolic Metabolites in Plasma and Thigh Meat of Chickens Supplemented with Grape Byproducts. J Agric Food Chem 2019;67:4463–71. https://doi.org/10.1021/acs.jafc.9b00222. NO Ministerio de Economía y Competitividad (España) NO Consejo Superior de Investigaciones Científicas NO Comunidad de Madrid DS Docta Complutense RD 18 abr 2025