RT Journal Article
T1 Brain derived neurotrophic factor (BDNF) polymorphisms and memory in healthy adults with university education
A1 Álvarez, Miguel Angel
A1 Zaldivar, Tatiana
A1 García-Morales, Leidy
A1 Pérez, Milvia
A1 Zayas, Mariesky
A1 Coromina, Julia C.
A1 Pita, Mariana
A1 Contreras, María José
A1 Manzanero Puebla, Antonio Lucas
AB The polymorphisms (C270T) and Val66Met of the BDNF gene are related to diverse cognitive processes in neurological and psychiatric conditions. But little is known about its relations with cognitive processes in healthy people. The present study explored the relationship of the C270T and Val66Met polymorphisms with implicit memory (semantic and perceptual priming tasks), semantic explicit memory (lexical selection), and episodic explicit memory (free recall). In total, 135 healthy volunteers between 20 and 60 years of age (M = 27.94, SD = 11.04), 92 women (M = 27.36, SD = 11.32), and 42 men (M = 29.21, SD = 10.42), participated in the study. One hundred and three of them completed the genetic study of C270T (36 males and 67 females), and 123 completed the Val66Met (38 males and 85 females). Results regarding ValMet polymorphism showed lower scores for MetMet in free recall. In relation to C270T, TT polymorphism performed better in the visual priming task than CT. The potential value as biomarkers of memory of these polymorphisms is discussed.
PB Spanish Society for Experimental Psychology
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/100341
UL https://hdl.handle.net/20.500.14352/100341
LA eng
NO Álvarez, M. A., Zaldivar, T., García-Morales, L., Pérez, M., Zayas, M., Coromina, J.C., Pita, M., Contreras, M. J., & Manzanero, A. L.(2023). Brain derived neurotrophic factor (BDNF) polymorphisms and memory in healthy adults with university education. Psicológica, 44(2): e15431. doi:10.20350/digitalCSIC/15431
DS Docta Complutense
RD 22 ene 2026