RT Journal Article
T1 The Advantage of Arriving First: Characteristic Times inFinite Size Populations of Error-Prone Replicators
A1 Marín Aguacil, Arturo
A1 Tejero Franco, Héctor
A1 Nuño Sanz, Juan Carlos
A1 Montero Carnerero, Francisco
AB We study the evolution of a finite size population formed by mutationally isolated lineages of error-prone replicators in a two-peak fitness landscape. Computer simulations are performed to gain a stochastic description of the system dynamics. More specifically, for different population sizes, we compute the probability of each lineage being selected in terms of their mutation rates and the amplification factors of the fittest phenotypes. We interpret the results as the compromise between the characteristic time a lineage takes to reach its fittest phenotype by crossing the neutral valley and the selective value of the sequences that form the lineages. A main conclusion is drawn: for finite population sizes, the survival probability of the lineage that arrives first to the fittest phenotype rises significantly.
PB Public Library of Science
SN 1932-6203
YR 2013
FD 2013-12
LK https://hdl.handle.net/20.500.14352/33941
UL https://hdl.handle.net/20.500.14352/33941
LA eng
NO Ministerio de Economía y Competitividad
DS Docta Complutense
RD 10 may 2025