RT Journal Article
T1 Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction
A1 Vicent, Lourdes
A1 Álvarez García, Jesús
A1 Vazquez Garcia, Rafael
A1 González Juanatey, José R.
A1 Rivera, Miguel
A1 Segovia, Javier
A1 Pascual Figal, Domingo
A1 Bover, Ramón
A1 Worner, Fernando
A1 Fernández Avilés, Francisco
A1 Ariza Sole, Albert
A1 Martínez-Sellés D Oliveira Soares, Manuel
AB Our aim was to determine the prognostic impact of coronary artery disease (CAD) on heart failure with reduced ejection fraction (HFrEF) mortality and readmissions. From a prospective multicenter registry that included 1831 patients hospitalized due to heart failure, 583 had a left ventricular ejection fraction of <40%. In total, 266 patients (45.6%) had coronary artery disease as main etiology and 137 (23.5%) had idiopathic dilated cardiomyopathy (DCM), and they are the focus of this study. Significant differences were found in Charlson index (CAD 4.4 ± 2.8, idiopathic DCM 2.9 ± 2.4, p < 0.001), and in the number of previous hospitalizations (1.1 ± 1, 0.8 ± 1.2, respectively, p = 0.015). One-year mortality was similar in the two groups: idiopathic DCM (hazard ratio [HR] = 1), CAD (HR 1.50; 95% CI 0.83–2.70, p = 0.182). Mortality/readmissions were also comparable: CAD (HR 0.96; 95% CI 0.64–1.41, p = 0.81). Patients with idiopathic DCM had a higher probability of receiving a heart transplant than those with CAD (HR 4.6; 95% CI 1.4–13.4, p = 0.012). The prognosis of HFrEF is similar in patients with CAD etiology and in those with idiopathic DCM. Patients with idiopathic DCM were more prone to receive heart transplant.
PB MDPI
SN 2077-0383
YR 2023
FD 2023-04-21
LK https://hdl.handle.net/20.500.14352/103560
UL https://hdl.handle.net/20.500.14352/103560
LA eng
NO Vicent, L.; Álvarez-García, J.; Vazquez-Garcia, R.; González-Juanatey, J.R.; Rivera, M.; Segovia, J.; Pascual-Figal, D.; Bover, R.; Worner, F.; Fernández-Avilés, F.; et al. Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction. J. Clin. Med. 2023, 12, 3028. https://doi.org/ 10.3390/jcm12083028
NO Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares.
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 6 abr 2025