RT Journal Article
T1 Urine Bactericidal Activity against Escherichia coli Isolates Exhibiting Different Resistance Phenotypes/Genotypes in an In Vitro Pharmacodynamic Model Simulating Urine Concentrations Obtained after Oral Administration of a 400-Milligram Single Dose of Cefditoren-Pivoxil
A1 Sevillano Fernández, David
A1 Aguilar, Lorenzo
A1 Alou Cervera, Luis
A1 Gimenez, María José
A1 Torrico, Martha
A1 González Hidalgo, Natalia
A1 Cafini, Fabio
A1 Relaño, María Teresa
A1 Coronel, Pilar
A1 Prieto Prieto, José
AB Activity of simulated cefditoren urinary concentrations was determined against seven Escherichia coli isolates. Bactericidal activity was obtained from 4 to 24 h against TEM-1 (penicillinase production/hyperproduction), TEM-34 (IRT-6), and TEM-116 (extended-spectrum beta-lactamase [ESBL]) and from 6 to 8 h against SHV/TEM-116 (ESBL) but never against SHV/TEM-1 (ESBL). Extension of bactericidal activity depended on the resistance genotype/phenotype tested.
PB American Society for Microbiology
SN 0066-4804
YR 2008
FD 2008-03
LK https://hdl.handle.net/20.500.14352/107129
UL https://hdl.handle.net/20.500.14352/107129
LA eng
NO Sevillano D, Aguilar L, Alou L, Giménez M, Torrico M, González N, Cafini F, Relaño M, Coronel P, Prieto J 2008. Urine Bactericidal Activity against Escherichia coli Isolates Exhibiting Different Resistance Phenotypes/Genotypes in an In Vitro Pharmacodynamic Model Simulating Urine Concentrations Obtained after Oral Administration of a 400-Milligram Single Dose of Cefditoren-Pivoxil. Antimicrob Agents Chemother 52:. https://doi.org/10.1128/aac.01247-07
NO Tedec-Meiji Farma S.A.
DS Docta Complutense
RD 17 abr 2025