RT Journal Article
T1 Sex-Related Disparities in the Incidence and Outcomes of Community-Acquired Pneumonia among Type 2 Diabetes Patients: A Propensity Score-Matching Analysis Using the Spanish National Hospital Discharge Database for the Period 2016–2019
A1 López De Andrés, Ana Isabel
A1 Jiménez García, Rodrigo
A1 Hernández Barrera, Valentín
A1 Miguel Díez, Javier De
A1 Miguel Yanes, José María De
A1 Carabantes Alarcón, David
A1 Zamorano León, José Javier
A1 Sanz Rojo, Sara
A1 López Herranz, Marta
AB (1) Background: To analyze incidence, clinical characteristics, procedures, and in-hospital outcomes among patients hospitalized with community-acquired pneumonia (CAP) according to the presence of T2DM in Spain (2016–2019) and to assess the role of gender among those with T2DM.(2) Methods: Using the Spanish National Hospital Discharge Database, we estimated hospitalized CAP incidence. Propensity score matching was used to compare population subgroups.(3) Results: CAP was coded in 520,723 patients, of whom 140,410 (26.96%) had T2DM. The hospitalized CAP incidence was higher in patients with T2DM (both sexes) (IRR 4.25; 95% CI 4.23–4.28). The hospitalized CAP incidence was higher in men with T2DM than in women with T2DM (IRR 1.46; 95% CI 1.45–1.47). The hospitalized CAP incidence among T2DM patients increased over time; however, the in-hospital mortality (IHM) decreased between 2016 and 2019. IHM was higher among non-T2DM men and women than matched T2DM men and women (14.23% and 14.22% vs. 12.13% and 12.91%; all p < 0.001, respectively), After adjusting for confounders, men with T2DM had a 6% higher mortality risk than women (OR 1.06; 95% CI 1.02–1.1).(4) Conclusions: T2DM is associated with a higher hospitalized CAP incidence and is increasing overtime. Patients hospitalized with CAP and T2DM have lower IHM. Male sex is a significant risk factor for mortality after CAP among T2DM patients.
PB MPDI
SN 2077-0383
YR 2021
FD 2021-09-02
LK https://hdl.handle.net/20.500.14352/4793
UL https://hdl.handle.net/20.500.14352/4793
LA eng
NO López De Andrés, A. I., Jiménez García, R., Hernández Barrera, V. et al. «Sex-Related Disparities in the Incidence and Outcomes of Community-Acquired Pneumonia among Type 2 Diabetes Patients: A Propensity Score-Matching Analysis Using the Spanish National Hospital Discharge Database for the Period 2016–2019». Journal of Clinical Medicine, vol. 10, n.o 17, septiembre de 2021, p. 3975. DOI.org (Crossref), https://doi.org/10.3390/jcm10173975.
NO Instituto de Salud Carlos III (ISCIII) / FEDER
DS Docta Complutense
RD 11 may 2025