TY  - JOUR
AU  - Sebastián Serrano, Álvaro
AU  - De Diego García, Laura
AU  - Engel,Tobias
AU  - Henshall, DC
AU  - Díaz Hernández, Miguel
PY  - 2018
DO  - 10.3389/fphar.2018.00170
UR  - https://hdl.handle.net/20.500.14352/114537
T2  - Frontiers in Pharmacology
AB  - Hypophosphatasia (HPP) is a rare heritable metabolic bone disease caused by hypomorphic mutations in the ALPL (in human) or Akp2 (in mouse) gene, encoding the tissue-nonspecific alkaline phosphatase (TNAP) enzyme. In addition to skeletal and dental...
LA  - eng
M2  - 1
PB  - Frontiers Media
KW  - Tissue-nonspecific alkaline phosphatase (TNAP)
KW  - Adenosine 5′-triphosphate (ATP)
KW  - Hypophosphatasia (HPP)
KW  - P2X7 receptor (P2X7R)
KW  - Pannexin 1 (Panx1)
KW  - Seizure
KW  - Epilepsy
KW  - Connexins
TI  - Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels
TY  - journal article
VL  - 9
ER  -