TY - JOUR AU - Moreno-Delgado, David AU - Puigdellívol, Mar AU - Moreno, Moreno AU - Rodríguez-Ruiz, Mar AU - Botta, Joaquín AU - Gasperini, Paola AU - Chiarlone, Anna AU - Howell, Lesley A. AU - Scarselli, Marco AU - Casadó, Vicent AU - Cortés, Antoni AU - Ferré, Sergi AU - Guzmán, Manuel AU - Lluís, Carmen AU - Alberch, Jordi AU - Canela, Enric I. AU - Ginés, Silvia AU - McCormick, Peter J. PY - 2020 DO - 10.7554/eLife.51093 SN - ESSN 2050-084X UR - https://hdl.handle.net/20.500.14352/6622 T2 - eLife AB - Early Huntington’s disease (HD) include over-activation of dopamine D1 receptors (D1R), producing an imbalance in dopaminergic neurotransmission and cell death. To reduce D1R over-activation, we present a strategy based on targeting complexes of D1R... LA - eng M2 - 1 PB - eLife Sciences Publications KW - Dopamine KW - Histamine KW - Huntington’s disease TI - Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington’sdisease TY - journal article VL - 9 ER -