TY  - JOUR
AU  - Minutti, Carlos
AU  - Jackson-Jones, Lucy
AU  - García-Fojeda García-Valdecasas, María Belén
AU  - Knipper, Johanna 
AU  - Sutherland, Tara
AU  - Logan, Nicola
AU  - Ringqvist, Emma
AU  - Guillamat-Prats, Raquel
AU  - Ferenbach, David
AU  - Artigas, Antonio
AU  - Stamme, Cordula 
AU  - Chroneos, Zissis 
AU  - Zaiss, Dietmar 
AU  - Casals Carro, María Cristina
AU  - Allen, Judith 
PY  - 2017
DO  - 10.1126/science.aaj2067
SN  - 0036-8075
UR  - https://hdl.handle.net/20.500.14352/94512
T2  - Science
AB  - The type 2 immune response controls helminth infection and maintains tissue homeostasis but can lead to allergy and fibrosis if not adequately regulated. We have discovered local tissue-specific amplifiers of type 2-mediated macrophage activation. In...
AB  - Local macrophage clean-up.Infection, especially by helminths or bacteria, can cause tissue damage (see the Perspective by Bouchery and Harris). Minutti et al. studied mouse models of helminth infection and fibrosis. They expressed surfactant protein A...
LA  - eng
M2  - 1076
PB  - American Association for the Advancement of Science
KW  - Tissue repair
KW  - Macrophages
KW  - Surfactant protein A
KW  - C1q
KW  - Interleukin-4
KW  - Type 2 immune response
KW  - Alternative activation
KW  - Defense collagens
KW  - Proliferation
TI  - Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver
TY  - journal article
VL  - 356
ER  -