RT Journal Article
T1 Uvemaster: A mobile app-based decision support system for the differential diagnosis of uveitis
A1 Gegúndez Fernández, José Antonio
A1 Fernández Vigo, Jose I.
A1 Díaz Valle, David
A1 Méndez Fernández, Rosalía
A1 Cuiña Sardiña, Ricardo
A1 Santos Bueso, Enrique Miguel
A1 Benítez Del Castillo Sánchez, José Manuel
AB PURPOSE. To examine the diagnostic accuracy and performance of Uvemaster, a mobile application (app) or diagnostic decision support system (DDSS) for uveitis. The app contains a large database of knowledge including 88 uveitis syndromes each with 76 clinical items, both ocular and systemic (total 6688) and their respective prevalences, and displays a differential diagnoses list (DDL) ordered by sensitivity, specificity, or positive predictive value (PPV). METHODS. In this retrospective case-series study, diagnostic accuracy (percentage of cases for which a correct diagnosis was obtained) and performance (percentage of cases for which a specific diagnosis was obtained) were determined in reported series of patients originally diagnosed by a uveitis specialist with specific uveitis (N = 88) and idiopathic uveitis (N = 71), respectively. RESULTS. Diagnostic accuracy was 96.6% (95% confidence interval [CI], 93.2–100). By sensitivity, the original diagnosis appeared among the top three in the DDL in 90.9% (95% CI, 84.1–96.6) and was the first in 73.9% (95% CI, 63.6–83.0). By PPV, the original diagnosis was among the top DDL three in 62.5% (95% CI, 51.1–71.6) and the first in 29.5% (95% CI, 20.5– 38.6; P < 0.001). In 71 (31.1%) patients originally diagnosed with idiopathic uveitis, 19 new diagnoses were made reducing this series to 52 (22.8%) and improving by 8.3% the new rate of diagnosed specific uveitis cases (performance = 77.2%; 95% CI, 71.1–82.9). CONCLUSIONS. Uvemaster proved accurate and based on the same clinical data was able to detect more cases of specific uveitis than the original clinician only–based method.
PB The Association for Research in Vision and Ophthalmology
YR 2017
FD 2017-10-01
LK https://hdl.handle.net/20.500.14352/112280
UL https://hdl.handle.net/20.500.14352/112280
LA eng
NO Gegundez-Fernandez JA, Fernandez-Vigo JI, Diaz-Valle D, et al. Uvemaster: a mobile app-based decision support system for the differential diagnosis of uveitis. Invest Ophthalmol Vis Sci. 2017;58:3931– 3939. DOI:10.1167/iovs.17-21493
DS Docta Complutense
RD 10 abr 2025