RT Journal Article
T1 Histological findings in experimentally infected male calves with chronic besnoitiosis
A1 Diezma Díaz, Carlos
A1 Tabanera De Lucio, Enrique
A1 Ferré Pérez, Ignacio
A1 Pizarro Díaz, Manuel
A1 González Huecas, Marta
A1 Blanco Murcia, Francisco Javier
A1 Ortega Mora, Luis Miguel
A1 Álvarez García, Gema
AB The histological findings associated to Besnoitia besnoiti infection were exhaustively studied in target tissues from experimentally and chronically infected calves. Calves were inoculated with 106 bradyzoites via intravenous, subcutaneous and intradermal route. Visible pathognomonic sclera cysts were observed in all infected animals. Tissue cysts were more abundant and lesions were more frequent in calves inoculated via intradermal. The most parasitized tissues were skin, including scrotum (40.81% of positive samples), nostril and nasal turbinate. Tissue cysts were already fully developed as the average tissue cyst diameter was 181.20 μm. Microscopic lesions were mainly detected in skin samples, followed by reproductive and upper respiratory tracts. Mild lesions compatible with both acute (thrombus, oedema and inflammation) and chronic besnoitiosis (skin lesions, hyperkeratosis and dilated sweat glands) coexisted. Vascular damage and inflammation were more frequently observed in skin (including scrotum) followed by testicular parenchyma, epididymis and pampiniform plexus. Histological findings evidenced a subclinical chronic besnoitiosis.
PB Elsevier
SN 0304-4017
SN 1873-2550
YR 2020
FD 2020-04-20
LK https://hdl.handle.net/20.500.14352/116355
UL https://hdl.handle.net/20.500.14352/116355
LA eng
NO C. Diezma-Díaz, E Tabanera, I. Ferre, M. Pizarro-Díaz, M. González-Huecas, J. Blanco-Murcia, L.M. Ortega-Mora, G. Álvarez-García, Histological findings in experimentally infected male calves with chronic besnoitiosis, Veterinary Parasitology, Volume 281, 2020, 109120, https://doi.org/10.1016/j.vetpar.2020.109120.
NO Contributions:C. Diezma-Díaz: Writing - original draft, Investigation, Formal analysis. E Tabanera: Methodology, Investigation. I. Ferre: Conceptualization, Formal analysis, Supervision. M. Pizarro-Díaz: Methodology, Investigation. M. González-Huecas: Methodology, Investigation. J. Blanco-Murcia: Resources, Supervision. L.M. Ortega-Mora: . G. Álvarez-García: Conceptualization, Writing - review & editing, Supervision, Project administration, Funding acquisition.
NO Ministerio de Economía y Competitividad (España)
NO Comunidad de Madrid
DS Docta Complutense
RD 11 abr 2025