TY  - JOUR
AU  - Michalska Dziama, Patrycja
AU  - Buendia, Izaskun
AU  - Duarte, Pablo
AU  - Fernandez-Mendivil, Cristina
AU  - Negredo, Pilar
AU  - Cuadrado, Antonio
AU  - Lopez, Manuela
AU  - Leon, Rafael
PY  - 2019
DO  - 10.1016/j.phrs.2019.104597
UR  - https://hdl.handle.net/20.500.14352/100863
T2  - Pharmacological Research
AB  - Neuroinflammation is increasingly associated to the onset and progression of neurodegenerative diseases. Furthermore, several lines of evidence have demonstrated the capacity of aberrant protein aggregates to activate the immune response, accelerating...
LA  - eng
PB  - Elsevier
KW  - ITH12674
KW  - Neuroinflammation
KW  - Neurodegenerative diseases
KW  - Antiinflammatory properties
KW  - MD2 antagonist
KW  - TLR4 inhibitor
KW  - NRF2
KW  - Nuclear factor (erythroid-derived 2)-like 2
KW  - Multi-target
TI  - Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization
TY  - journal article
ER  -