RT Journal Article
T1 Fetal Development of the Incisive Canal, Especially of the Delayed Closure Due to the Nasopalatine Duct: A Study Using Serial Sections of Human Fetuses
A1 Kim, Ji Hyun
A1 Oka, Kyoko
A1 Jin, Zhe Wu
A1 Murakami, Gen
A1 Rodríguez Vázquez, José Francisco
A1 Ahn, Sung Woo
A1 Hwang, Hong Pil
AB The incisive canal of the incisive bone or premaxilla is a narrow bony canal through which pass the nasopalatine nerve and its concomitant vessels. However, its fetal development remains obscure. To assess its development, serial frontal sections of the heads of 26 human fetuses, of gestational age 9–20 weeks (crown-rump length, 46–183 mm), were examined. The nerve initially passed through a wide loose tissue space, but after ossification of the upper part of the incisive bone at 12–15 weeks, the canal became narrow and filled with tight fibrous tissue. Canals in seven fetuses were dilated and open unilaterally or bilaterally. In two of these seven fetuses, a nasopalatine duct passed through the canal and connected the nasal cavity to a central lumen of the paramedian epithelial pearl in the incisive fossa (not to an oral cavity). Even if the canal was closed, the duct was likely to remain above and below the closed part. Paramedian pearls were present in all specimens larger than 110 mm (15 weeks), with or without association of midline pearls. These paramedian pearls usually protruded toward and/or extended into the dilated or open canal, suggesting that these pearls, not any primitive oronasal communication pathway, contributed to keeping the canal open. The dilated canal, located on the superomedial side of the second and third teeth buds, seemed to be usually closed by further ossification. Even in fetuses, the nasopalatine duct seemed to be a variant or unusual phase of development temporally occurring after normal palate fusion
PB Wiley
SN 1932-8486
YR 2017
FD 2017-01-27
LK https://hdl.handle.net/20.500.14352/109937
UL https://hdl.handle.net/20.500.14352/109937
LA eng
NO Kim, J. H., Oka, K., Jin, Z. W., Murakami, G., Rodríguez-Vázquez, J. F., Ahn, S. W., & Hwang, H. P. (2017). Fetal Development of the Incisive Canal, Especially of the Delayed Closure Due to the Nasopalatine Duct: A Study Using Serial Sections of Human Fetuses. Anatomical record (Hoboken, N.J. : 2007), 300(6), 1093–1103. https://doi.org/10.1002/ar.23521
DS Docta Complutense
RD 4 abr 2025