TY  - JOUR
AU  - González Cofrade, Laura
AU  - Green, Jack P
AU  - Cuadrado Berrocal, Irene
AU  - Amesty, Angel
AU  - Oramas-Royo, Sandra
AU  - Brough, David
AU  - Estevez-Braun, Ana
AU  - Hortelano, Sonsoles
AU  - Heras Polo, Beatriz De Las
PY  - 2023
DO  - 10.1016/j.bioorg.2023.106362
UR  - https://hdl.handle.net/20.500.14352/119539
T2  - Bioorganic Chemistry
AB  - Dysregulated inflammasome activity, particularly of the NLRP3 inflammasome, is associated with the development of several inflammatory diseases. The study of molecules directly targeting NLRP3 is an emerging field in the discovery of new therapeutic...
LA  - eng
M2  - 106362
PB  - Elsevier
KW  - Nor-friedelane triterpenes
KW  - Maytenus retusa
KW  - NLRP3 inflammasome
KW  - ASC
KW  - Pyroptosis
KW  - IL-1β
KW  - Macrophages
TI  - Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors
TY  - journal article
VL  - 132
ER  -