RT Journal Article T1 Polymorphisms in twelve candidate genes are associated with growth, muscle lipid profile and meat quality traits in eleven European cattle breeds A1 Sevane Fernández, Natalia A1 Armstrong, Eileen A1 Wiener, Pam A1 Pong Wong, Ricardo A1 Dunner Boxberger, Helene Susana AB Current customers’ demands focus on the nutritional and sensory quality of cattle meat. Candidate gene approach allows identification of genetic polymorphisms that have a measurable effect on traits of interest. The aim of this work is to identify new molecular markers for beef production through an association study using 27 candidate genes and 314 purebred bulls from 11 European cattle breeds. Twelve genes were found associated with different lipid and meat quality traits, and among these stand out the considerable effect of CAST on fatness score, CGGBP1 on growth traits, HSPB1 on the percentage of lauric acid (12:0) and phospholipid docosahexaenoic acid (DHA 22:6 n − 3), RORA on the ratio of light absorption (K) to light scattering (S) (K/S), and TNFA on lightness (L*). Most of these traits are related to post-mortem muscle biochemical changes, which are key factors controlling meat quality and consumers’ acceptance. Also, the variations produced on muscle fatty acid profiles, such as those of AANAT, CRH, CSN3, HSPB1, and TNFA, give insights into the genetic networks controlling these complex traits and the possibility of future improvement of meat nutritional quality. PB Springer Link SN 0301-4851 YR 2014 FD 2014 LK https://hdl.handle.net/20.500.14352/92746 UL https://hdl.handle.net/20.500.14352/92746 LA eng NO Sevane N, Armstrong E, Wiener P, Pong Wong R, Dunner S, the GemQual Consortium (2014) Polymorphisms in twelve candidate genes are associated with growth, muscle lipid profile and meat quality traits in eleven European cattle breeds. Molecular Biology Reports 41, 4721-4731. NO European Comission DS Docta Complutense RD 18 abr 2025