TY - JOUR AU - Coronas Serna, Julia María AU - Fernández-Acero Bascones, Teresa AU - Molina, María AU - Cid, Víctor J. PY - 2018 DO - 10.15698/mic2018.12.660 SN - 2311-2638 UR - https://hdl.handle.net/20.500.14352/13360 T2 - Microbial cell (Graz, Austria) AB - Phosphatidylinositol 3-kinase (PI3K) is a key regulator of phosphoinositide-dependent signaling in mammalian cells and its dysfunction is related to multiple syndromes, including cancer. By heterologous expression in , we have developed a humanized... LA - eng M2 - 545 PB - Shared Science Publishers KW - PI3K KW - P110α KW - Phosphoinositides KW - Saccharomyces cerevisiae KW - Humanized yeast KW - Heterologous expression KW - Fluorescent reporter KW - Eisosomes KW - Septins KW - Kinase inhibitors TI - A humanized yeast-based toolkit for monitoring phosphatidylinositol 3-kinase activity at both single cell and population levels. TY - journal article VL - 5 ER -