RT Journal Article
T1 Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features
A1 Carrasco Perera, José Luis
A1 Díaz Marsa, Marina Francisca
A1 Pastrana, Jose I.
A1 Molina, Rosa
A1 Brotons, Loreto
A1 López-Ibor Alcocer, María Inés
A1 López-Ibor Aliño, Juan José
AB Hypothalamic–pituitary–adrenal (HPA) axis sensitivity was investigated in 32 non-medicated patients with borderline personality disorder without comorbid post-traumatic syndromes and in 18 normal individuals using a modified dexamethasone suppression test (0.25 mg). Enhanced cortisol suppression was found in the patients v. controls (P < 0.05) and the percentage of participant's with non-suppression was smaller in the patient (34%) than in the control group (89%) (P < 0.01). Baseline cortisol levels in the patients were also lower than in the controls (P < 0.05). The 0.25 mg dexamethasone suppression test reveals increased feedback inhibition of the HPA in borderline personality disorder.
PB Cambridge University Press
SN 0007-1250
SN 1472-1465
YR 2018
FD 2018-01-02
LK https://hdl.handle.net/20.500.14352/116874
UL https://hdl.handle.net/20.500.14352/116874
LA eng
NO Carrasco JL, Díaz-Marsá M, Pastrana JI, et al. Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features. British Journal of Psychiatry. 2007;190(4):357-358. doi:10.1192/bjp.bp.106.022590
DS Docta Complutense
RD 16 abr 2025