RT Journal Article
T1 Near-infrared lifetime nanothermometry detects microwave-induced brain heating
A1 Liyan Ming, 
A1 José Lifante, 
A1 Ginés Lifante Pedrola, 
A1 Daniel Ortega, 
A1 Erving Ximendes, 
A1 Riccardo Marin, 
A1 Julio Ramiro Bargueño, 
A1 Daniel Jaque, 
A1 Rubio Retama, Benito Jorge
A1 Zabala Gutiérrez, Irene
AB In modern environments, the brain is continuously exposed to numerous external stimuli, including the microwave radiation used in telecommunication technologies. It has been suggested that the absorption of this radiation by brain tissue can induce local heating. Because brain temperature influences neural activity, metabolism, and overall brain function, microwave-induced heating raises concerns over the safety of such technologies. Proper evaluation of the risks associated with microwave-based technologies thus requires accurate quantification of heating in deep organs without disrupting their physiology. This study, demonstrates that microwave-induced brain heating can be remotely monitored in vivo via luminescence thermometry using near-infrared luminescent silver sulfide (Ag2 S) nanoparticles. Their temperature-dependent luminescence lifetime is a reliable thermometric parameter for the measurement of absolute brain temperature. The in vivo results offer direct, real-time evidence of brain heating (up to 4 °C) under telecom exposure conditions (3 GHz). Moreover, they establish lifetime thermometry as a reliable, minimally invasive approach for investigating thermoregulation in deep tissues even under external electromagnetic stimulation
PB Wiley
YR 0025
FD 0025-11-06
LK https://hdl.handle.net/20.500.14352/131036
UL https://hdl.handle.net/20.500.14352/131036
LA eng
NO Ming L, Lifante J, Pedrola GL, et al. Near‐Infrared Lifetime Nanothermometry Detects Microwave‐Induced Brain Heating. Advanced Optical Materials 2025;13:e02319. https://doi.org/10.1002/adom.202502319
NO Ministerio de Ciencia, Innovación y Universidades
NO Comunidad de Madrid
DS Docta Complutense
RD 17 mar 2026