TY - JOUR AU - Louloudes-Lázaro, Andrés AU - Rojas, José M. AU - García García, Isabel AU - Rodríguez Martín, Daniel AU - Morel, Esther AU - Martín, Verónica AU - Sevilla, Noemí PY - 2023 DO - 10.3389/fimmu.2023.1255803 SN - 1664-3224 UR - https://hdl.handle.net/20.500.14352/121127 T2 - Frontiers in Immunology AB - Bluetongue virus (BTV) is an arbovirus transmitted by the bite of infected Culicoides midges that affects domestic and wild ruminants producing great economic losses. The infection induces an IFN response, followed by an adaptive immune response that... LA - eng PB - Frontiers KW - Orbivirus KW - T cells KW - PD-1/PD-L1 checkpoint KW - Transcriptomic KW - Monocytes KW - B cells TI - Comprehensive immune profiling reveals that Orbivirus infection activates immune checkpoints during acute T cell immunosuppression TY - journal article VL - 14 ER -