RT Journal Article T1 Pharmaceuticals released from senior residences: occurrence and risk evaluation A1 Lacorte, Silvia A1 Luis, Silvia A1 Gómez-Canela, Cristian A1 Sala-Comorera, Teresa A1 Courtier, Audrey A1 Roig, Benoit A1 Oliveira-Brett, Ana A1 Joannis-Cassan, Claire A1 Aragonés Tapia, Juan Ignacio A1 Poggio Lagares, Lucía A1 Noguer, Tierry A1 Lima, María Luisa A1 Barata, Carlos A1 Calas-Blanchard, Carole AB One of the main pursuits, yet most difficult, in monitoring studies is to identify the sources of environmental pollution. In this study, we have identified health-care facilities from south European countries as an important source of pharmaceuticals in the environment. We have estimated that compounds consumed in by the elderly and released from effluents of senior residences can reach river waters at a concentration higher than 0.01 μg/L, which is the European Medicines Agency (EMA) threshold for risk evaluation of pharmaceuticals in surface waters. This study has been based on five health institutions in Portugal, Spain, and France, with 52 to 130 beds. We have compiled the pharmaceuticals dispensed on a daily base and calculated the consumption rates. From 54.9 to 1801 g of pharmaceuticals are consumed daily, with laxatives, analgesics, antiepileptics, antibiotics, and antidiabetic agents being the main drug families administered. According to excretion rates, dilution in the sewerage system, and elimination in wastewater treatment plants, macrogol, metformin, paracetamol, acetylcysteine, amoxicillin, and gabapentin, among others, are expected to reach river waters. Finally, we discuss the risk management actions related to the discharge of pharmaceuticals from senior residences to surface waters. PB Springer Link SN 0944-1344 YR 2018 FD 2018-03 LK https://hdl.handle.net/20.500.14352/98190 UL https://hdl.handle.net/20.500.14352/98190 LA eng NO Lacorte, S., Luis, S., Gómez-Canela, C., Sala-Comorera, T., Courtier, A., Roig, B., Oliveira-Brett, A., Joannis-Cassan, C., Aragonés, J. I., Poggio, L., Noguer, T., Lima, L., Barata, C., & Calas-Blanchard, C. (2018). Pharmaceuticals released from senior residences: occurrence and risk evaluation. Environmental Science and Pollution Research, 25(7), 6095-6106. https://doi.org/10.1007/s11356-017-9755-1. DS Docta Complutense RD 18 abr 2025