TY - JOUR AU - Romero Picó, Amparo AU - Garrido Novelle, Marta AU - Al-Massadi, Omar AU - Beiroa, Daniel AU - Tojo, Marta AU - Heras, Violeta AU - Ruíz Pino, Francisco AU - Senra, Ana AU - López, Miguel AU - Blouet, Clemence AU - Tena Sempere, Manuel AU - Nogueiras, Rubén AU - Diéguez, Carlos PY - 2022 DO - 10.3390/ijms23063118 SN - 1661-6596 UR - https://hdl.handle.net/20.500.14352/94507 T2 - International Journal of Molecular Sciences AB - Weight gain is a hallmark of decreased estradiol (E2) levels because of menopause or following surgical ovariectomy (OVX) at younger ages. Of note, this weight gain tends to be around the abdomen, which is frequently associated with impaired metabolic... LA - eng M2 - 1 KW - Energy expenditure KW - Estrogens KW - Kappa-opioid KW - Obesity KW - p70S6K TI - Kappa-opioid receptor blockade ameliorates obesity caused by estrogen withdrawal via promotion of energy expenditure through mTOR pathway TY - journal article VL - 23 ER -