TY  - JOUR
AU  - Ruiz-Antoran, Belén
AU  - Sancho-López, Aranzazu
AU  - Cazorla-Calleja, Rosario
AU  - López-Pájaro, Luis Fernando
AU  - Leiva, Ágata
AU  - Iglesias-Escalera, Gema
AU  - Marín-Serrano, María Esperanza
AU  - Rincón-Ortega, Marta
AU  - Lara-Herguedas, Julián
AU  - Rossignoli-Palomeque, Teresa
AU  - Valiente-Rodríguez, Sara
AU  - González Marqués, Javier
AU  - Román-Riechmann, Enriqueta
AU  - Avendaño-Solá, Cristina
PY  - 2018
DO  - 10.1186/s13023-018-0891-6
SN  - 1750-1172
UR  - https://hdl.handle.net/20.500.14352/99340
T2  - Orphanet Journal of Rare Diseases
AB  - Background: Minocycline is an old tetracycline antibiotic that has shown antiinflammatory and antiapoptotic properties in different neurological disease mouse models. Previous single arm study in humans demonstrated benefits in individuals with...
LA  - eng
M2  - 144
PB  - BMC
KW  - Angelman syndrome
KW  - Treatment
KW  - Minocycline
KW  - Developmental changes
KW  - Pharmacological intervention
TI  - A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study)
TY  - journal article
VL  - 13
ER  -