RT Journal Article
T1 Thromboembolic risk in atrial fibrillation: Association between left atrium mechanics and risk scores. A study based on 3D wall-motion tracking technology
A1 Islas, Fabián
A1 Olmos, Carmen
A1 Vieira, Catarina
A1 De Agustín Loeches, José Alberto
A1 Marcos Alberca, Pedro
A1 Saltijeral, Adriana
A1 Almería, Carlos
A1 Rodrigo López, José Luis
A1 García Fernández, Miguel Ángel
A1 Macaya Miguel, Carlos
A1 Pérez De Isla, Leopoldo
AB Background/ObjectivesAtrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with a significantly high risk of stroke and systemic embolism. The aim of our study was to assess the association between left atrium (LA) mechanics measured by 3D wall-motion tracking (3DWMT) technology and the most common thromboembolic risk scores (CHADS2, CHA2DS2-VASc).MethodsA total of 101 consecutive patients with permanent AF referred were included. Conventional bidimensional (2D) LA parameters, and LA mechanics by means of 3DWMT were studied. Association between LA 2D and 3DWMT parameters and both risk scores was evaluated as well as its correlation with every component of the score individually.ResultsMean age was 78 ± 10 years. Mean CHADS2 was 2.7 ± 1.3 and mean CHA2DS2-VASc was 4.4 ± 1.7. Values of 2D and 3DWTM LA parameters were: 2D area 26.4 ± 9.7 cm2, 2D volume index 49.4 ± 10.1 mL/m2, 3DWMT left atrial emptying fraction (LAEF) 15.9 ± 8.4%, longitudinal strain 9.1 ± 4.5% and area strain 14.9 ± 8.8%. Linear regression analysis showed statistically significant correlation between LA longitudinal strain and LAEF with CHADS2 and CHA2DS2-VASc scores. For each 10% variation in longitudinal strain, CHADS2 and CHA2DS2-VASc scores change in 0.7 and 0.8 points, respectively.ConclusionsLeft atrial longitudinal strain and emptying fraction assessed by 3D WMT technology have correlation with both CHADS2 and CHA2DS2-VASc scores. Each 10% of variation in longitudinal strain represents a 0.7 and 0.8 points change in those risk scores. LA mechanics evaluation might provide additional value to risk scores and could be considered to be a predictor of stroke in patients with AF.
PB Wiley
SN 0742-2822
YR 2015
FD 2015-04-04
LK https://hdl.handle.net/20.500.14352/131392
UL https://hdl.handle.net/20.500.14352/131392
LA eng
NO Islas, F., Olmos, C., Vieira, C., De Agustín, J. A., Marcos-Alberca, P., Saltijeral, A., Almería, C., Rodrigo, J. L., García Fernández, M. A., Macaya, C., & Pérez de Isla, L. (2015). Thromboembolic risk in atrial fibrillation: association between left atrium mechanics and risk scores. A study based on 3D wall-motion tracking technology. Echocardiography (Mount Kisco, N.Y.), 32(4), 644–653. https://doi.org/10.1111/echo.12711
DS Docta Complutense
RD 26 feb 2026