TY  - THES
AU  - Billod, Jean-Marc
A3  - Martín-Santamaría, Sonsoles
PY  - 2019
UR  - https://hdl.handle.net/20.500.14352/16827
AB  - The heterodimeric complex, formed by Toll-Like Receptor 4 (TLR4) and its accessory protein Myeloid Differentiation factor 2 (MD-2) is responsible of activating the innate immune system when sensing the presence of particular pathogen-associated...
AB  - El complejo heterodimérico, formado por el receptor Toll-like 4 (Toll-like receptor 4, TLR4) y su proteína accesoria, el Myeloid Differentiation factor 2 (MD-2), es responsable de activar la respuesta del sistema inmune innato cuando detecta la...
LA  - eng
PB  - Universidad Complutense de Madrid
KW  - TLR4
KW  - molecular recognition
KW  - drug design
KW  - Myeloid Differentiation factor 2 (MD-2)
KW  - nnate immune system
KW  - pathogen-associated molecular patterns (PAMPs)
KW  - lipopolysaccharides (LPS)
KW  - reconocimiento molecular
KW  - diseño de fármacos
KW  - sistema inmune innato
KW  - patógenos (pathogen associated molecular patterns
KW  - PAMPs)
KW  - lipopolisacáridos (lipopolisaccharides
KW  - LPS)
TI  - TLR4 modulation: molecular recognition studies and drug design by molecular modelling
T2  - Modulación del TLR4 : estudios de reconocimiento molecular y diseño de fármacos por modelado molecular
M3  - doctoral thesis
ER  -