TY  - JOUR
AU  - Solares, Isabel
AU  - Izquierdo Sánchez, Laura
AU  - Morales Conejo, Montserrat
AU  - Jericó, Daniel
AU  - Castelbón, Francisco Javier
AU  - Córdoba, Karol Marcela
AU  - Sampedro, Ana
AU  - Lumbreras Bermejo, Carlos Juan
AU  - Moreno Aliaga, María Jesús
AU  - Enríquez de Salamanca, Rafael
AU  - Berraondo, Pedro
AU  - Fontanellas, Antonio
PY  - 2021
DO  - 10.3390/biomedicines9030255
SN  - 2227-9059
UR  - https://hdl.handle.net/20.500.14352/7391
T2  - Biomedicines
AB  - Acute porphyria attacks are associated with the strong up-regulation of hepatic heme synthesis and over-production of neurotoxic heme precursors. First-line therapy is based on carbohydrate loading. However, altered glucose homeostasis could affect...
LA  - eng
M2  - 255
PB  - MDPI
KW  - Acute intermittent porphyria
KW  - Carbohydrate loading therapy
KW  - Insulin resistance
KW  - Hyperinsulinemia
KW  - Fast-acting insulin
KW  - Experimental liver-targeted insulin
TI  - High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach
TY  - journal article
VL  - 9
ER  -