RT Journal Article
T1 Detection of selection signatures for agonistic behaviour in cattle
A1 Eusebi, Paulina
A1 Cortés Gardyn, Óscar
A1 Carleos, Carlos
A1 Dunner Boxberger, Helene Susana
A1 Cañón Ferreras, Francisco Javier
AB The identification of genomic regions including signatures of selection produced by domestication and its subsequent artificial selection processes allows the understanding of the evolution of bovine breeds. Although several studies describe the genomic variability among meat or milk production cattle breeds, there are limited studies orientated towards bovine behavioural features. This study is focused on mapping genomic signatures of selection which may provide insights of differentiation between neutral and selected polymorphisms. Their effects are studied in the Lidia cattle traditionally selected for agonistic behaviour compared with Spanish breeds showing tamed behaviour. Two different approaches, BayeScan and SelEstim, were applied using genotypic 50K SNP BeadChip data. Both procedures detected two genomic regions bearing genes previously related to behavioural traits. The frequencies of the selected allele in these two regions in Lidia breed were opposite to those found in the tamed breeds. In these genomic regions, several putative genes associated with enriched metabolic pathways related to the behavioural development were identified, as neurochondrin gene (NCDN) or glutamate ionotropic receptor kainate type subunit 3 (GRIK3) both located at BTA3 or leucine-rich repeat and Ig domain containing 2 (LINGO2) and phospholipase A2-activating protein (PLAA) at BTA8.
PB Wiley
SN 0931-2668
YR 2018
FD 2018
LK https://hdl.handle.net/20.500.14352/100136
UL https://hdl.handle.net/20.500.14352/100136
LA eng
NO Eusebi PG, Cort es O,Carleos C, Dunner S, Ca~n on J. Detection of selectionsignatures for agonistic behaviour in cattle.J AnimBreed Genet. 2018;135:170–177.https://doi.org/10.1111/jbg.12325
DS Docta Complutense
RD 17 ago 2024