RT Journal Article
T1 Development of a polarization imaging method to detect paraffin‐embedded pathology tissues before applying other techniques
A1 Sijilmassi, Ouafa
A1 López Alonso, José Manuel
A1 Río Sevilla, Aurora, del
A1 Barrio Asensio, María del Carmen
AB The present article describes the development of a technique, applied to paraffin‐embedded tissues, which uses three different wavelengths of monochromatic light (λ1 = 445 nm, λ2 = 540 nm and λ3 = 660 nm) for the measures of the degree of polarization, degree of linear polarization, degree of circular polarization and birefringence, all obtained from measurements of Stokes parameters by using polarized light. The goal of this study was to detect changes in developing embryonic mouse eye when pregnant mice fed diets without folic acid for variable periods compared with a healthy control group. We present a biomedical diagnostic technique based on polarized light detection applied to paraffin‐embedded tissues to visualize the structural damage to aid us in the diagnosis before applying other techniques. Through this method, we can visualize and identify which parts of the tissue were altered with respect to the control group.
PB WILEY‐VCH Verlag GmbH
SN 1864-063X
YR 2020
FD 2020-09-27
LK https://hdl.handle.net/20.500.14352/6681
UL https://hdl.handle.net/20.500.14352/6681
LA eng
NO Received: 17 July 2020; Revised: 6 September 2020; Accepted: 24 September 2020
NO Ministerio de Economía y Competitividad (MINECO)
NO Ministerio de Sanidad, Servicios Sociales e Igualdad
NO Universidad Complutense de Madrid/Banco de Santander
DS Docta Complutense
RD 27 abr 2024