TY - JOUR AU - Valhondo Falcón, Margarita AU - Marco, Isabel AU - Martín-Fontecha Corrales, María Del Mar AU - Vázquez Villa, María Del Henar AU - Ramos Atance, José Antonio AU - Berkels, Reinhard AU - Lauterbach, Thomas AU - Benhamú Salama, Bellinda AU - López Rodríguez, María Luz PY - 2013 DO - 10.1021/jm400766k SN - 0022-2623 UR - https://hdl.handle.net/20.500.14352/114421 T2 - Journal of Medicinal Chemistry AB - We report the synthesis of new compounds 4–35 based on two different openings (A and B) of the chromane ring present in the previously identified 5-HT1A receptor (5-HT1AR) ligand 3. The synthesized compounds were assessed for binding affinity,... LA - eng M2 - 7851 PB - ACS Publications KW - Serotonin 5-HT1A Receptor KW - GPCR KW - Agonists KW - Neuropathic pain KW - Antinociceptive effect TI - New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo TY - journal article VL - 56 ER -